TABLE 3.
Incidence Rate, Relative Hazard (RH), and Population Attibutable Fraction (PAF) for Heart Failure Among Risk Groups, the Atherosclerosis Risk in Communities (ARIC) Study, 1987–2005
Risk Profile based on 4-factor score* | No. of Subjects at Risk | No. of Subjects Developing Heart Failure | Incidence Rate† | Adjusted RH (95% CI)‡ | PAF, % |
---|---|---|---|---|---|
Total sample | |||||
All optimal risk factors | 665 | 12 | 1.1 | 0.18 (0.10–0.32 | 0.0 |
Borderline risk factors only | 4,028 | 177 | 2.7 | 0.35 (0.30–0.41) | 6.5 |
Having any elevated risk factors | 8,767 | 1,155 | 8.6 | 1.0§ | 70.6 |
African Americans | |||||
All optimal risk factors | 103 | 4 | 2.4 | 0.28 (0.10–0.74) | 0.0 |
Borderline risk factors only | 638 | 33 | 3.2 | 0.31 (0.22–0.44) | 0.8 |
Having any elevated risk factors | 2,700 | 444 | 11.2 | 1.0§ | 66.7 |
Whites | |||||
All optimal risk factors | 562 | 8 | 0.8 | 0.16 (0.08–0.31) | 0.0 |
Borderline risk factors only | 3,390 | 144 | 2.6 | 0.36 (0.30–0.43) | 9.5 |
Having any elevated risk factors | 6,067 | 711 | 7.6 | 1.0§ | 69.6 |
This 4-factor score included blood pressure, plasma cholesterol, diabetes and smoking, as categorized in Table 1.
Crude incidence rate per 1000 person-years
RH adjusted for age and sex, plus race for the total sample.
The reference group for the RH is those having any elevated risk factor.