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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: J Immunol. 2008 Dec 1;181(11):8027–8035. doi: 10.4049/jimmunol.181.11.8027

Figure 7. Increased phosphorylation of JNK in COX-2 transgenic mice treated with LPS/D-GalN.

Figure 7

The COX-2 transgenic mice and matched wild type mice were sacrificed 4 hours after LPS/D-GalN injection. The liver tissues were homogenized and the extracted proteins were subjected to SDS-PAGE and Western blot analysis using the antibody against phospho-JNK (Cell Signaling Technology, Danvers, MA). Western blot for β-actin was used as the loading control. The lower panel represents the ratio between phosphorylated p54-JNK2 and β-actin by densitometry analysis. *ρ<0.01 compared to wild type mice treated LPS/D-GalN or COX-2 Tg mice treated with saline.