Table 1.

Survival Rate of wild type, COX-2 transgenic and EP₁ knockout mice after LPS/GlaN injection

Hours after injection	Wild Type Number of viable mice	COX-2 Transgenic Number of viable mice	EP1 Knockout Number of viable mice	Saline Injection Number of viable mice
5	16	16	15	8
6	16	10	15	8
7	14	6	13	8
8	8	4	9	8
9	2	0	7	8
10	2	0	3	8
11	0	0	3	8
12	0	0	1	8
24	0	0	1	8

The COX-2 transgenic, EP₁ knockout and wild type mice at 6−8 weeks of age received a single intraperitoneal injection of LPS/GalN. The animals were closely monitored for activity and mortality was documented at hourly intervals (up to 24 hours).