Figure 3. Enhanced survival after STS is dependent upon NF-κB signaling.
(A) Survival curve of E. coli-infected dif-key flies after AL (grey line), STS (black line) or STS and L-NAME-treatment (red line). Graphs show mean survival (±s.e.) from three independent experiments. (B) Total mean bacterial density of dif-key flies after infection with E. coli after AL (grey bars), STS (black bars) or treatment with L-NAME and STS (white bars). The total mean c.f.u. per fly (±s.e.) from three individual experiments are shown. Double asterisk (**) indicates a statistically significant difference in value from all other values (Student's t-Test; P = <0.01). (C) Quantification of cellular nitric oxide in E. coli-infected dif-key flies (white bars). Graphs show relative NO concentration (to uninfected flies [black bars]) of 15 male flies from three independent experiments (±s.e.). Asterisk (*) indicates statistically significant difference in the mean value in comparison to the other mean values presented in the graph as determined by Student's t-Test (P = <0.05).