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. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Virus Res. 2008 Aug 23;137(2):198–205. doi: 10.1016/j.virusres.2008.07.010

Figure 1. Dose dependent weight loss and decreased thymocyte number in C57BL/6 mice following infection with VACV-Ova.

Figure 1

C57BL/6 mice were infected i.n. with low, high, or lethal doses of VACV-Ova or were mock-infected (PBS). A) Changes in body weight for mock-infected mice (circles) or mice infected with low (squares), high (triangles), lethal (diamonds) doses were calculated as a percentage of initial body weight. B) Thymocyte numbers were calculated by determining percentage of the population that was double positive (CD8+CD4+) and single positive (CD8+ or CD4+) at day 7 p.i. and multiplying by the total number of recovered cells. Percentages were obtained following gating on the live lymphocyte population. Each data point or bar represents the mean of 5 mice ± SEM. * P < 0.05 compared to low dose-infected mice.