Skip to main content
. Author manuscript; available in PMC: 2009 Nov 1.
Published in final edited form as: Virus Res. 2008 Aug 23;137(2):198–205. doi: 10.1016/j.virusres.2008.07.010

Figure 4. Infection with a high and lethal dose of VACV-Ova resulted in increased apoptosis in B cells in the spleen.

Figure 4

C57BL/6 mice were infected i.n. with low (5×102), high (5×104), or lethal (5×105) dose of VACV-Ova or were mock-infected (PBS) and spleens harvested at day 7. A) Representative flow cytometric data showing active caspase 3 staining of CD19+ cells. The number in the dot plot is the percentage of CD19+ cells that stained positive for active caspase 3+. B) Averaged data showing the percent of CD19+ cells staining positive for active caspase 3. * = significant increase, p<0.05; # = significant decrease, p<0.05.