Table 1.

Physiological variables

	Vehicle (n=11)	LAU-0901 (n=10)
Before MCAo (15 min)
Rectal temperature (°C)	36.8 ± 0.07	36.6 ± 0.10
Cranial temperature (°C)	36.7± 0.14	36.4 ± 0.11
pH	7.43 ± 0.01	7.42 ± 0.01
PO2, mm Hg	113 ± 6	122 ± 5
PCO2, mm Hg	40.5 ± 1.13	39 7 ± 0.91
Plasma glucose, mg/dL	167 ± 8	165 ± 10
Body weight (g)	294 ± 8	328 ± 7
During MCAo (15 min)
Rectal temperature (°C)	37.0 ± 0.10	36.8 ± 0.09
Cranial temperature (°C)	36.7 ± 0.15	36.6 ± 0.09
pH	7.42 ± 0.01	7.40 ± 0.01
PO2, mm Hg	99 ± 4	101 ± 3
PCO2, mm Hg	41.1 ± 0.97	43.0 ± 0.89
Plasma glucose, mg/dL	146 ± 6	150 ± 6
After MCAo (2h)
Rectal temperature (°C)	38.3 ± 0.25	38 0 ± 0.31
Cranial temperature (°C)	37.4 ± 0.24	36.9 ± 0.29
During chronic survival
Rectal temperature (°C).	38.0± 0.17	37.5 ± 0.61
Body weight (g), 1 day	269 ± 7	300 ± 8
Rectal temperature (°C).	37.1 ± 0.26	37.8 ± 0.13
Body weight (g), 2 days	261 ± 14	297 ± 10
Rectal temperature (°C).	37.2 ± 0.18	37.7 ± 0.16
Body weight (g), 3 days	259 ± 8	296 ± 10*
Rectal temperature (°C).	37.5 ± 0.15	37.6 ± 0.13
Body weight (g), 1 week	286 ± 10	332 ± 10*
Rectal temperature (°C).	37.5 ± 0.12	37.7 ± 0.10
Body weight (g), 2 weeks	328 ± 13	389 ± 8*
Rectal temperature (°C).	37.2 ± 0.30	37.5 ± 0.18
Body weight (g), 3 weeks	370 ± 13	428 ± 9*
Rectal temperature (°C).	37.7 ± 0.21	37.5 ± 0.12
Body weight (g), 4 weeks	397 ± 9	452 ± 9*

Values are mean ± SEM

MCAo, middle cerebral artery occlusion

^*different from vehicle group (p<0.05, Student’s t-test).