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. 2009 Feb 12;4(2):e4447. doi: 10.1371/journal.pone.0004447

Figure 3. Following intense activation of AchRs or mGluRs the ISO can be associated with cyclic paroxysms.

Figure 3

A. Simultaneous LFP and unit recording from the VB in the presence of 100 µM Cch showing an ISO at ∼0.03 Hz. The underlined section is enlarged below. Additional enlargements of the sections marked 1 and 2 are shown further below, as indicated, and reveal that LFP activity consists of a mixture of fast runs at ∼10 Hz corresponding to periods of tonic firing (1), and rhythmic SW/PSW complexes at ∼4 Hz (2) which are related to unusually powerful HT burst activity. In 1 and 2, the underlined sections are expanded to the immediate right. B. Simultaneous LFP and unit recording from the LGN in the presence of 200 µM trans-ACPD showing an ISO at ∼0.004 Hz. The underlined section is enlarged below. Additional enlargements of the sections marked 1 and 2 are shown further below, as indicated, and reveal that field activity consists of rhythmic SW/PSW complexes at ∼3 Hz which are closely related to HT burst activity in the simultaneously recorded TC neuron.