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. 2009 Feb 10;4(2):e4416. doi: 10.1371/journal.pone.0004416

Figure 1. Presence of GS in human foreskin of children and regional variations in its distribution revealed in co-localization studies with GFAP, or with SMAA.

Figure 1

(A–D) Expression of GS (A) and GFAP (B) and merged micrograph of GS and GFAP (C) immune reaction in human foreskin sections. (D–F) Expression of GS (D) and SMAA (E) and merged micrograph of GS and SMAA immune reaction (F) in a human skin section. The line connecting the D–F clearly shows strong expression of SMAA (E) in stratum granulosum and its absence of stratum corneum. The latter is strongly stained for GS (D). GS and SMAA merge at the interface of stratum corneum boarder and stratum granulosum (F). Binding of specific antibodies was visualized with FITC-conjugated goat anti-rabbit IgG and Cy3-conjugated goat anti-mouse IgG. Blue arrows point to stratum corneum, magenta arrows to stratum basale white arrows to fibroblasts and yellow arrows to small and middle-sized vessels. Scale bar: A–D, H 200 μm; E–G 100 μm.