Figure 4.
Partial duplication of human SCN2A. (A) A 78-bp duplication (hatched box) consisting of the last 48 bp of exon 24 and the first 30 bp of intron 24 was identified 1.3 kb downstream of the splice donor site of exon 24. (B) The duplicated segment (underlined) is 96% identical to the corresponding sequence at the exon 24/intron 24 junction. Filled boxes, exons; hatched box, duplicated segment. Distances are shown in kilobases. Exonic sequences appear in uppercase and intronic sequences appear in lowercase. Dots indicate sequence identity between the exon 24-intron 24 (X24/I24) junction and intron 24 (I24).