. Author manuscript; available in PMC: 2009 Feb 9.

Published in final edited form as: Hum Mol Genet. 2007 Apr 15;16(SPEC):R14–R20. doi: 10.1093/hmg/ddl486

Table 1.

Colorectal cancer risk among HNPCC patients based on TGFBR1*6A status: adjusted ORs for the associations between MMR mutation status and TGFBR1 genotype

TGFBR1 genotype		MMR mutation status (N = 208) N (positive/negative)	Crude ORs for MMR – (95% Cl)^a
Dominant model
	9A/9A	115/43	1.00
	9A/6A or 6A/6A	29/21	1.94 (1.00–3.75)
Additive model
	9A/9A	115/43	1.00
	9A/6A	28/17	1.62 (0.81–3.26)
	6A/6A	1/4	10.70 (1.16–98.4)
Recessive model
	9A/9A or 9A/6A	143/60	1.00
	6A/6A	1/4	9.53 (1.04–87.1)

ORs were adjusted for age at diagnosis and gender. Nine subjects with unknown age or gender were excluded from the analysis.