Table 3.
Jadad score calculation for quality assessment of included trials
| Study (reference) | Trial described as randomized | Randomization method was described and appropriate | Double blind | Double blinding method described and appropriate | Withdrawals and dropouts described | Jadad score |
|---|---|---|---|---|---|---|
| Prevention trials | ||||||
| Akamatsu 2005 (21) | Yes | Yes | No | No | Yes | 3 |
| Brenner 1995 (23) | Yes | Yes | Yes | Yes | Yes | 5 |
| Hayashi 2003 (24) | Yes | No | No | No | Yes | 2 |
| Hayashida 2000 (25) | Yes | No | No | No | Yes | 2 |
| Kurnik 1990 (27) | Yes | No | Yes | Yes | Yes | 4 |
| Kurnik 1998 (28) | Yes | No | Yes | Yes | Yes | 4 |
| Langrehr 1997 (30) | Yes | No | No | No | Yes | 2 |
| Sezai 2000 (35) | Yes | No | Yes | Yes | Yes | 4 |
| Sezai 2006 (36) | Yes | No | Yes | Yes | Yes | 4 |
| Sezai 2006a (37) | Yes | No | No | No | Yes | 2 |
| Sezai 2007 (38) | Yes | No | No | No | Yes | 2 |
| Treatment trials | ||||||
| Allgren 1997 (22) | 1 | 1 | 1 | 1 | 1 | 5 |
| Herbert 1999 (26) | 1 | 0 | 1 | 1 | 1 | 4 |
| Kuse 1996 (29) | 1 | 0 | 1 | 1 | 1 | 4 |
| Lewis 2000 (31) | 1 | 1 | 1 | 1 | 1 | 5 |
| Meyer 1997 (32) | 1 | 0 | 1 | 1 | 1 | 4 |
| Meyer 1999 (33) | 1 | 0 | 1 | 1 | 1 | 4 |
| Rahman 1994 (34) | 1 | 0 | 0 | 0 | 1 | 2 |
| Sward 2004 (39) | 1 | 1 | 1 | 1 | 1 | 5 |