Table 6.
Multivariable odds ratios (ORs) of TMA pathology with 95% confidence intervals (CIs) in allogeneic transplant recipients compared to no evidence of TMA or renal thrombus (n = 196)
| Factor | OR | 95% CI | P |
|---|---|---|---|
| Patient/donor sex | |||
| other | 1.0 | — | — |
| female/male | 2.8 | 1.2 to 6.7 | 0.02 |
| TBI conditioning (cGy) | |||
| none | 1.0 | — | — |
| ≤ 1200 | 1.8 | 0.7 to 4.7 | 0.24 |
| > 1200 | 2.6 | 1.1 to 6.2 | 0.02 |
| CSA dose per day (mg) | |||
| quartile 1 (0 to 99) | 1.0 | — | — |
| quartile 2 (100 to 167) | 1.0 | 0.4 to 2.8 | 0.95 |
| quartile 3 (168 to 279) | 1.4 | 0.5 to 3.7 | 0.47 |
| quartile 4 (280 to 2295) | 0.9 | 0.3 to 2.4 | 0.83 |
| Acute GVHD grade | |||
| 0, I | 1.0 | — | — |
| II to IV | 3.4 | 1.3 to 8.8 | 0.01 |
| Adenovirus infection | |||
| no | 1.0 | — | — |
| yes | 2.8 | 1.2 to 6.8 | 0.02 |