Table 5.
Mean results of 10 Monte Carlo microsimulations
Patient Outcomes | Estimated Glomerular Filtration Rate (eGFR) Reporting | Serum Creatinine Reporting | Mean Difference Using eGFR Reporting |
---|---|---|---|
Deaths | 4,627 | 4,640 | −13 |
Transitions from CKD (FN-CKD or TP-CKD) to ESRD | 1,259 | 1,288 | −29 |
Number of FP-CKD categorizations | 17,015 | 5,667 | 11,348 |
Patient-years spent in FN-CKD | 253 | 2,325 | −2,072 |
Patient-years spent in TP-CKD | 22,196 | 19,842 | 2,354 |
Each microsimulation was composed of 10,000 trials of 18 one-year cycles. Serum creatinine and eGFR measurements occurred once per cycle. CKD, chronic kidney disease, stages 3 to 4 (glomerular filtration rate 15 to 59 ml/min/1.73 m2); FN-CKD, false negative state for patient with chronic kidney disease, stages 3 to 4; TP-CKD, true positive state for patient with chronic kidney disease, stages 3 to 4; ESRD, end stage renal disease (glomerular filtration rate < 15 ml/min/1.73 m2); FP-CKD, false-positive state for patient with chronic kidney disease, stages 3 to 4.