Table 2.

Mean serum phosphate values for the ITT^a population during each study period: primary efficacy variable^b

Study Period	Placebo (n = 20)	Fermagate 1 g (n = 21)	Fermagate 2 g (n = 21)	Total (n = 62)
Current therapy
mean	1.482	1.554	1.556	1.531
SD	0.389	0.379	0.377	0.377
Baseline (washout)
mean	2.142	2.171	2.161	2.159
SD	0.466	0.548	0.379	0.462
During treatment
mean	2.209	1.715	1.467	1.790
SD	0.566	0.522	0.481	0.600
Change from baseline to during treatment
mean	0.066	−0.457	−0.695	−0.369
SD	0.331	0.520	0.323	0.508

^aITT, intent-to-treat.

^bValues given in mmol/L. Serum phosphate level during treatment with 1- and 2-g fermagate three times daily was significantly lower than either washout or in comparison with placebo-treated patients.