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Effect of Ko143 on intracellular accumulation of mitoxantrone in MCF7 and MCF7/MX100 cells. Bars represent mean ± S.D. of three determinations. **P < 0.001, compared to MCF7 cells. *P < 0.05 and ***P < 0.001, compared to those without 1 μM Ko143. Empty bars represent vesicle controls, solid bars represent treatment with Ko143.
