Table 3.
Difference in CD4 counts and HIV-1 RNA levels in treatment arm versus placebo arm.
| Average difference in CD4 count between albendazole and placebo groups at 12 weeks follow-up | (95%CI) | P value | Average difference in Log10 HIV-1 RNA between albendazole and placebo groups at 12 weeks follow-up | (95%CI) | P value | |
|---|---|---|---|---|---|---|
|
All ITT individuals (n=208) |
+37.0 cells/mm3 | (−4.6 to +78.7) | 0.08 | −0.11 log10 copies/mL | (−0.37 to +0.15) | 0.42 |
|
Ascaris lumbricoides (n=54) |
+109.0 cells/mm3 | (+38.9 to +179.0) | 0.003 | −0.54 log10 copies/mL | (−1.17 to +0.09) | 0.09 |
|
Hookworm (n=148) |
+11.9 cells/mm3 | (−36.6 to 60.3) | 0.63 | +0.001 log10 copies/mL | (−0.30 to +0.30) | 1.00 |
|
Trichuris trichiura (n=24) |
+35.6 cells/mm3 | (−135.3 to +206.5) | 0.67 | +0.31 log10 copies/mL | (−0.49 to +1.10) | 0.43 |
|
Mixed Infection (n=19) |
+24.2 cells/mm3 | (−124.0 to +172.5) | 0.73 | −0.32 log10 copies/mL | (−1.68 to +1.03) | 0.62 |