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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Pharmacol Rev. 2008 Jun 25;60(2):210–241. doi: 10.1124/pr.107.08002

Table 3.

Coronary Calcification in women participating in the CEEonly – arm of WHIa

Number of Participantsc
CEE n=537 Placebo n = 527 Odds Ratiod (95%CI)

CAC Scores (Agatston Units)
0 (referent)b 299 266 1.00
>0 238 261 0.81 (0.64–1.03)
<10 (referent)b 348 302 1.00
≥ 10 189 225 0.73 (0.57–0.93)
<100 (referent)b 448 408 1.00
≥100 89 119 0.68 (0.50–0.93)

Vasomotor Symptomse
 Yes 23.3% 26.5%
 No 76.7% 73.5%
a

Derived from Tables 1 and 2 of (Manson et al., 2007).

b

Referent groups are all participants within the stated CAC range.

c

Numbers of individuals who were at least 80% adherent to CEE or placebo for at least 5 years.

d

Odds ratios were calculated for the CEE group compared to the Placebo group.

e

Percentage of women reporting moderate-to-severe vasomotor symptoms in each assigned group prior to initiation of treatment (baseline).