Table 3.
Univariate relationships between plasma CML and other factors with estimated glomerular filtration rate in adults, aged ≥65 years, at enrollment in the InCHIANTI Study
| Characteristic | Beta | SE | P | |
|---|---|---|---|---|
| Age, years1 | 70-74 | -2.78 | 1.42 | 0.05 |
| 75-79 | -5.76 | 1.52 | 0.0002 | |
| 80-84 | -10.61 | 1.85 | <0.0001 | |
| 85-89 | -12.29 | 2.08 | <0.0001 | |
| ≥90 | -13.47 | 2.58 | <0.0001 | |
| Sex, male | 7.20 | 1.07 | <0.0001 | |
| Education, years | 0.44 | 0.16 | 0.006 | |
| Smoking status2 | Former | 2.63 | 1.25 | 0.04 |
| Current | 4.75 | 1.62 | 0.004 | |
| Body mass index (kg/m2) | -0.10 | 0.13 | 0.44 | |
| Plasma CML (ng/mL), per 1 SD | -3.91 | 0.52 | <0.0001 | |
| Mini-Mental Exam Score <24 | -5.43 | 1.18 | <0.0001 | |
| Hypertension | 0.08 | 1.98 | 0.94 | |
| Angina | -3.15 | 2.57 | 0.22 | |
| Peripheral artery disease | -3.44 | 2.26 | 0.13 | |
| Congestive heart failure | -10.58 | 2.39 | <0.0001 | |
| Stroke | -2.63 | 2.47 | 0.29 | |
| Diabetes mellitus | 1.55 | 1.62 | 0.34 | |
| Depression | -5.28 | 1.30 | <0.0001 | |
| Cancer | -7.45 | 2.20 | 0.0007 | |
1
Reference category is age 65-69 years.
2
Reference category is never a smoker.