Table 4.
Model adjusted for age, sex | Model adjusted for age, sex, education, smoking, MMSE | Model adjusted for age, sex, education, smoking, MMSE and chronic diseases3 | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Beta | SE | P | Beta | SE | P | Beta | SE | P | ||
Plasma CML1,2 (ng/mL) | All Subjects (n = 1008) | -3.29 | 0.51 | <0.0001 | -3.24 | 0.51 | <0.0001 | -2.77 | 0.51 | <0.0001 |
Subjects Without Diabetes (n = 879) | -3.20 | 0.53 | <0.0001 | -3.17 | 0.53 | <0.0001 | -2.98 | 0.54 | <0.0001 | |
Subjects Who Were Current Nonsmokers (n = 871) | -3.32 | 0.56 | <0.0001 | -3.30 | 0.56 | <0.0001 | -2.73 | 0.56 | <0.0001 |
Separate multivariate linear regression models shown for plasma CML in which estimated glomerular filtration rate (mL/min/1.73 m2) is the dependent variable.
Beta expressed per 1 SD of plasma CML (1 SD = 110 ng/mL).
Chronic diseases were congestive heart failure, stroke, depression, and cancer.