. Author manuscript; available in PMC: 2010 Feb 1.

Published in final edited form as: Eur J Nutr. 2008 Nov 24;48(1):38–44. doi: 10.1007/s00394-008-0757-0

Table 5.

Separate multivariate linear regression models of the relationship of plasma CML at enrollment with estimated glomerular filtration rate in adults, aged ≥65 years, at three and six years of follow-up in the InCHIANTI Study

A. Estimated GFR at Three-Year Follow-Up
		Model adjusted for age, sex, baseline eGFR			Model adjusted for age, sex, baseline eGFR, education, smoking, MMSE			Model adjusted for age, sex, baseline eGFR, education, smoking, MMSE and chronic diseases³
		Beta	SE	P	Beta	SE	P	Beta	SE	P
Plasma CML¹,² (ng/mL)	All Subjects (n = 735)	-2.62	0.61	<0.0001	-2.62	0.61	<0.0001	-2.54	0.61	<0.0001
	Subjects Without Diabetes (n = 648)	-2.76	0.65	<0.0001	-2.76	0.66	<0.0001	-2.71	0.65	<0.0001
	Subjects Who Were Current Nonsmokers (n = 619)	-2.56	0.66	0.0002	-2.51	0.66	0.0002	-2.43	0.65	0.0002

B. Estimated GFR at Six-Year Follow-Up
		Model adjusted for age, sex, baseline eGFR			Model adjusted for age, sex, baseline eGFR, education, smoking, MMSE			Model adjusted for age, sex, education, smoking, MMSE and chronic diseases³
		Beta	SE	P	Beta	SE	P	Beta	SE	P
Plasma CML¹,² (ng/mL)	All Subjects (n = 643)	-1.18	0.70	0.09	-1.16	0.70	0.10	-1.21	0.70	0.08
	Subjects Without Diabetes (n = 567)	-1.46	0.76	0.05	-1.43	0.76	0.06	-1.49	0.76	0.05
	Subjects Who Were Current Nonsmokers (n = 556)	-1.38	0.76	0.07	-1.39	0.76	0.06	-1.46	0.76	0.05

Separate multivariate linear regression models shown for plasma CML in which estimated glomerular filtration rate (mL/min/1.73 m²) is the dependent variable.

Beta expressed per 1 SD of plasma CML (1 SD = 110 ng/mL).

Chronic diseases were congestive heart failure, stroke, depression, and cancer.