TABLE I.

Microarray fold-change values (mean ± SD, p < 0.05) for interferon-associated genes that are induced ≥2 fold in response to BP exposure and mitigated by chlorophyllin

Accession No	Gene Symbol	Gene Description	BP alonea	BP+CHLNb	Pre CHLN and Post BPc	Pre CHLN, Post BP+CHLNd
NM_002462	MX1	Interferon-inducible protein p78 (mouse)	7.5 ± 0.58	1.5 ± 0.34	0.9 ± 0.01	0.7 ± 0.03
NM_005101	G1P2	Interferon, alpha-inducible protein	7.2 ± 0.96	1.1 ± 0.38	0.5 ± 0.02	0.4 ± 0.08
NM_001548	IFIT1	Interferon-induced protein with tetratricopeptide repeats 1	6.3± 0.38	0.9 ± 0.53	0.9 ± 0.54	0.3 ± 0.03
NM_003641	IFITM1	Interferon induced transmembrane protein 1	4.0 ± 0.03	1.0 ± 0.06	1.4 ± 0.17	1.0 ± 0.06
NM_001549	IFIT4	Interferon-induced protein with tetratricopeptide repeats 4	2.4 ± 0.37	0.7 ± 0.04	0.8 ± 0.12	0.8 ± 0.04
NM_005532	IFI27	Interferon, alpha-inducible protein 27	3.3 ± 0.58	1.3 ± 0.10	0.6 ± 0.23	1.0 ± 0.21
NM_006332	IFI30	Interferon, gamma-inducible protein 30	2.2 ± 0.09	1.3 ± 0.07	1.2 ± 0.11	1.2 ± 0.05
NM_022873	G1P3	Interferon, alpha-inducible protein	3.3 ± 0.06	1.1 ± 0.37	0.7 ± 0.02	0.7 ± 0.05

^aBP Alone = cells were exposed to BP alone for 24 h.

^bBP+CHLN = cells were exposed to BP along with CHLN for 24 h; differences in expression levels between BP alone and BP + CHLN were statistically significant.

^cPre CHLN and Post BP = cells were exposed to CHLN for 24 h, washed and then incubated with BP for 24 h.

^dPre CHLN and Post BP+CHLN= cells were exposed to CHLN for 24 h, washed and then exposed to BP and CHLN for 24 h.