. Author manuscript; available in PMC: 2009 Mar 1.

Published in final edited form as: Environ Mol Mutagen. 2009 Mar;50(2):134–144. doi: 10.1002/em.20449

TABLE III.

Microarray fold-change (mean ± SD, p < 0.05) values for metabolism genes that were induced in response to BP exposure and mitigated by chlorophyllin

Accession No.	Gene Symbol	Gene Description	BP alone^a	BP+CHLN^b	Pre CHLN and Post BP^c	Pre CHLN, and Post BP+CHLN^d
NM_000104	CYP1B1	Cytochrome P450, family 1, subfamily B1	16.5 ± 1.53	9.3 ± 1.42	7.8 ± 0.59	6.4 ± 0.58
NM_000499	CYP1A1	Cytochrome P450, family 1, subfamily A1	12.2 ± 0.12	6.3 ± 0.96	6.8 ± 1.47	5.1 ± 0.22
NM_025163	SMP3	SMP3 mannosyl-transferase	7.7 ± 1.46	3.2 ± 0.20	2.3 ± 0.57	2.1 ± 0.92
NM_000903	NQO1^*	NAD(P)H dehydrogenase,quinone1	3.0 ± 0.19	2.4 ± 0.28	1.9 ± 0.03	1.9 ± 0.11
NM_017436	A4GALT	Alpha 1,4-galactosyltransferase	7.0 ± 0.12	4.3 ± 1.27	4.1 ± 0.95	5.4 ± 0.37
NM_002534	OAS1	2′,5′-oligoadenylate synthetase 1,	3.0 ± 0.01	0.7 ± 0.15	0.9 ± 0.03	0.6 ± 0.16
NM_002535	OAS2	2′-5′-oligoadenylate synthetase 2,	3.2 ± 0.25	0.5 ± 0.17	0.8 ± 0.09	1.5 ± 0.59

^a,b,c,dExposure conditions were as described in Methods and Table I.

CHLN alone induced NQO1 2.0 ± 0.19 (by RT-PCR).