Table II.

Clinical and laboratory outcomes

	Baseline	6 months	12 months
Modified Rodnan skin score*	20.6 ± 4.4 (9−31/19)	20.2 ± 5.5 (5−45.5/17)	21.1 ± 5.2 (8−45.5/17)
Pulmonary Function testing
Forced vital capacity (% predicted)	89.2 ± 10.8 (62−119)	92.7 ± 10.3 (53−120)
DLCO (% predicted)	79.7 ± 8.3 (61−107)	77.8 ± 7.5 (52−95)
Health Assessment Questionnaire
Disability Index	0.67 ± 0.32 (0−2.0)	0.64 ± 0.36 (0−2.25)	0.55 ± 0.33 (0−2.25)
VAS	0.73 ± 0.26 (0−1.875)	0.53 ± 0.21 (0−1.5)	0.56 ± 0.21 (0.03−1.5)
Immunoglobulins
IgM	107 ± 25 (15−172)	86 ± 24 (9−172)	86 ± 24 (11−172)
IgG	1106 ± 197 (756−2210)	1066 ± 173 (696−1970)	1021 ± 181 (588−1970)
IgA	270 ± 100 (61−539)	288 ± 105 (58−546)	274 ± 94 (58−532)
Sedimentation Rate	27.9 ± 11.7 (2−69)	20.5 ± 7.8 (6−40)	17.0 ± 6.1 (6−38)
Exploratory Outcomes
B cell score	10.4 ± 4.6 (0−23)	3.4 ± 4.8 (0−30)
SMA score	49.5 ± 16.6 (6−81.5)	36.6 ± 16.6 (2−78)

^*Values represent the average ± 95% confidence limit (range)