Table 3. Concordance of degree of methylation of 5′CGI(s) in UCWBC samples and gene expression levels in FPT samples.

Gene Name	tau*	Confidence Interval	p-value
ACSL3	−0.45	[−0.76, −0.15]	<0.01
RAD21	−0.30	[−0.70, +0.09]	0.13
DUSP22	−0.31	[−0.66, +0.05]	0.09
SCD5	−0.11	[−0.49, +0.26]	0.55
SFMBT2	−0.23	[−0.57, +0.10]	0.18
WWOX	+0.22	[−0.11, +0.55]	0.20

Note: % of methylated cytosine in the CGI(s) (regions mark as BSPCR in Fig 2) was determined by bisulfite sequencing; levels of gene expression was measured as steady state transcript levels in FPT samples matched to UCWBC samples (n = 14) quantified by real time RT-PCR.

^*The Kendall tau coefficient was calculated between % of methylation and gene expression; negative sign indicates inverse relationship. The larger the negative value means greater negative correlation and statistical significance was determined by a 2-tailed test with p<0.05.