Table 5. Characteristics of Subjects (Number, % Column Total) by ACSL3 5′CGI methylation Status and Asthma Status Assayed by MSPCR (N = 56).
ACSL3 5′CGI Methylation Status | Methylated | Unmethylated | All | Odds Ratios (95% CI's) |
Asthma (% Yes with asthma)a | 11/28 (39%) | 4/28 (14%) | 15/56 (27%) | 3.9 (1.1, 14.3) |
Median PAH exposure with in each groupb (Min, Max) | 3.39 ng/m3 (1.11, 34.48) | 1.7 ng/m3 (0.49, 3.33) | 2.26 ng/m3 (0.49, 34.48) |
Note: ap = 0.03. OR = 3.9 measuring the odds of asthma given ACSL3 5′-CGI was methylated (M) verus unmethylated (U).
p<0.001 testing the equality of median PAH exposure levels between subjects with methylated and unmethylated ACSL3 5′CGI in their UCWBCs.