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. Author manuscript; available in PMC: 2009 May 15.
Published in final edited form as: J Immunol. 2008 May 15;180(10):6518–6526. doi: 10.4049/jimmunol.180.10.6518

Figure 8. p85 is required for Tim-1-mediated IL-2 production.

Figure 8

Purified CD4+ T cells from p85β or p85α/β deficient mice were stimulated in vitro with anti-CD3/CD28 antibodies (20 ng/ml and 0.5 μg/ml, respectively) and the indicated concentrations of Tim-1 antibody (A) or with anti-Tim-1 antibody alone (B). Supernatants were harvested after one day and analyzed by ELISA for IL-2. Error bars (obscured by the marker is most cases) indicate standard deviation for triplicate points within a single experiment, which is representative of three that were performed.