Fig. 1.

Rotation rates and striatal l-dopa or DA concentrations after stereotactic injection of pHSVth, pSHVlac, or PBS into the partially denervated striatum (14). (A) The rats were tested at various times (14) for the apomorphine-induced rotation rate, and the values shown are the average percent of the baseline rotation rate for each group. (B) Striatal l-dopa concentrations were measured by microdialysis (15) after perfusion with NSD 1015 as an indication of striatal TH activity (16). (C) Striatal DA levels were measured by microdialysis in low K⁺ (3 mM) and after perfusion with high K⁺ (56 mM) (15).