. Author manuscript; available in PMC: 2009 Sep 15.

Published in final edited form as: Transplantation. 2008 Sep 15;86(5):647–651. doi: 10.1097/TP.0b013e3181814e76

Table 2.

Cerebrospinal fluid characteristics in patients with central nervous system cryptococcal lesions

Variable ^*	Parenchymal lesions (n=6)	Meningeal lesions (n=8)	Hydrocephalus (n=2)	Significance level (3-way)
Serum antigen titer	1:256	1:512	1:64^†	0.08
	(1:128–1:1024)	(1:64 –1:1024)
CSF characteristics
CSF antigen titer	1:32	I:768	1:2^†	0.015
	(1:16–1:64)	(1:256–1:1,024)
Opening pressure	21 (16 –25)	24 (13– 29)	19^†	0.95
WBC per mm³	130 (25 – 210)	119 (67 – 172)	194 (58–330)	0.93
Protein mg/dL	164 (60 – 227)	204 (87 – 479)	125 (110 –191)	0.72
Glucose mg/dL	41 (31 – 59)	32 (19 – 41)	61 (61 – 81)	0.22
Positive culture	83% (5/6)	100% (8/8)	50% ^¶ (1/2)	0.11

Values represent median and interquartile range

CSF= Cerebrospinal fluid, WBC= White blood cell count

^†

Serum cryptococcal antigen was available in 1/2 patients. CSF antigen level was 1:2 in both patients

^¶

Number reflects culture positivity at baseline. Both patients had negative CSF cultures at onset of hydrocephalus.