Figure 9.
Developmental timeline of hair cell voltage-sensitive and mechanosensitive conductance acquisition. The mean maximal conductance is plotted as a function of embryonic stage (bottom axis). The top axis plots conductance acquisition as a function of hair cell age. The 4 nS calibration bar applies below the dashed line, and the 20 nS calibration bar applies above the line. The inset shows a family of currents recorded from a second-wave E19 hair cell evoked by 100 msec steps from -104 to 36 mV in 20 mV increments. Based on the expression of small delayed rectifier (IDR), inward rectifier (IK1), and sodium (INa) currents, we estimate this cell was ∼3 d old (arrow).