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. Author manuscript; available in PMC: 2009 Feb 10.
Published in final edited form as: J Neurophysiol. 2006 Jul 19;96(5):2364–2376. doi: 10.1152/jn.00523.2006

FIG. 9. TEA lowered the threshold of low- and high-threshold neurons and shifted their sensitive ranges to lower frequencies.

FIG. 9

A: TEA application lowered the threshold for action potential firing, induced multiple action potentials, and increased AP width in a representative low-threshold neuron (control: black, TEA: gray, Cell 20030624A, P2). B: TEA lowered the threshold for action potential generation and broadened the width of the spike in a representative high-threshold neuron (control: black, TEA: gray, Cell 20030715A, P1). C and D: tuning curves for low- (C) and high- (D) threshold neurons. In the presence of TEA, both neurons had a lower threshold and fired action potentials at lower frequencies relative to controls (Low-threshold: Cell 20030702D, P2; high-threshold: Cell 20030709C, P3).