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. Author manuscript; available in PMC: 2009 Dec 1.

Published in final edited form as: Surgery. 2008 Dec;144(6):956–962. doi: 10.1016/j.surg.2008.08.027

Treatment with VPA (4a) and SBHA (4b) limits growth of PC-12 pheochromocytoma cells. PC-12 cells were treated with the indicated concentrations of HDAC inhibitors for up to 6 days, and cell viability was determined by the MTT colorimetric growth assay. Points represent mean +/− SE. All treatments are significantly different from control as soon as day 2 (* = P < 0.01, ** = P < 0.001, one-way ANOVA). VPA, valproic acid. SBHA, suberoyl bis-hydroxamic acid.

Treatment with VPA (4a) and SBHA (4b) limits growth of PC-12 pheochromocytoma cells. PC-12 cells were treated with the indicated concentrations of HDAC inhibitors for up to 6 days, and cell viability was determined by the MTT colorimetric growth assay. Points represent mean +/− SE. All treatments are significantly different from control as soon as day 2 (* = P < 0.01, ** = P < 0.001, one-way ANOVA). VPA, valproic acid. SBHA, suberoyl bis-hydroxamic acid.