TABLE 1.

Vital parameters for LDLR^−/− mice

	Total Cholesterol	Triglycerides	VLDLc	LDLc	HDLc	Non-HDLc:HDLc	Mass	Aortic Root Atherosclerosis
All mice (n = 321)	1500 ± 587	639 ± 444	668 ± 451	718 ± 216	110 ± 36	14.3 ± 8.8	29.2 ± 6.7	192,412 ± 107,491
Gender subgroups
Males (n = 164)	1543 ± 566	769 ± 487	629 ± 412	783 ± 224	124 ± 36	12.7 ± 7.3	33.6 ± 5.6	173,987 ± 96,662
Females (n = 157)	1449 ± 610	486 ± 328a	714 ± 491	641 ± 178a	93 ± 27a	16.1 ± 9.9a	24.1 ± 3.4a	214,174 ± 115,666a
Adaptive immunity subgroups
Competent (n = 148)	1695 ± 701	747 ± 506	797 ± 567	780 ± 242	109 ± 38	16.9 ± 10.9	30.4 ± 6.3	242,956 ± 112,934
Partial deficient (n = 55)	1439 ± 426	776 ± 402c	616 ± 242	712 ± 212	111 ± 36	13.0 ± 5.8	31.3 ± 7.0c	156,257 ± 80,309b,c
Deficient (n = 118)	1269 ± 362d	424 ± 262d	522 ± 280d	637 ± 143d	111 ± 32	11.4 ± 4.9d	26.6 ± 6.2d	143,310 ± 78,815d

All values are displayed as mean ± SD. Lipid parameters are expressed as mg/dl, mass in grams, and atherosclerosis as μm².

^aP < 0.01 for males vs. females.

^bP < 0.01 for adaptive immune competent vs. adaptive immune partial deficient.

^cP < 0.01 for adaptive immune partial deficient vs. adaptive immune deficient.

^dP < 0.01 for adaptive immune competent vs. adaptive immune deficient.