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(A) MEFs of all three genotypes show an increase in cyclin D levels after release from serum starvation. (B) MEFS of all three genotypes express cyclin-dependent kinase inhibitors p21, p27, and p16ink4 as they start to senesce. (C) After UV treatment MEFs of all genotypes induce p53, with an ≈10-fold increase in the A-MEFs compared with the other genotypes. A, androgenetic; P, parthenogenetic; BP, biparental.
