Table 1. Androgenetic MEFs and Igf2-transduced primary cells transform and form tumors at low passage.
| MEF | Cell line (passage no.) | Tumors, n | Tumor type |
|---|---|---|---|
| Biparental | MEF (p20) | 0/8 | |
| MEF (p44) | 8/8 | Sarcoma | |
| MEF (p16) + Igf2 Rv | 7/7 | Fibrosarcoma | |
| MEF (p8) M6Pr—/— + Igf2 Rv | 4/4 | Fibrosarcoma | |
| MEF (p16) Igf2—/— + Igf2 Rv | 3/3 | Fibrosarcoma | |
| Androgenetic | LB1.10 (p10) | 0/8 | |
| LB1.10 (p25) | 8/8 | Chondrosarcoma, sarcoma | |
| LB1.10 (p34) | 8/8 | Sarcoma | |
| LB Poly2 (p20) | 8/8 | Sarcoma | |
| Parthenogenetic | +Igf2 Rv (p16) | 3/3 | Fibrosarcoma |
Igf2 Rv, Igf2 retroviral vector.