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. 2008 Dec 12;9(Suppl 12):S3. doi: 10.1186/1471-2105-9-S12-S3

Table 5.

Results of our clustering-based approach on the human, mouse and rat genome data.

Human Mouse (All) Mouse (Distinct) Rat
# of predictions 374 381 359 276

# of TPs 196 172 165 101

# of real miRNAs 240 245 212 146

SE 81.67% 70.20% 77.83% 69.18%

Change in SE -7.91% -11.02% -8.09% -17.81%

PPV 52.41% 45.14% 45.96% 36.59%

Change in PPV +21.25% +14.81% +17.37% +15.94%

This table shows the SE and PPV obtained after our filtering approach is applied to the predicted candidates generated by ProMirII-g. The PPV is increased by more than 15% in all the three genomes. The SE is kept reasonably high as it is just slightly decreased by a percentage less than 10% in the human and mouse genomes.