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. 2009 Feb;133(2):171–188. doi: 10.1085/jgp.200810081

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© 2009 Gingrich et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jgp.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 8. — GABA potentiates channel blockade by PB. Plot of mean I_PB responses from rapidly perfused, outside-out cell-free macropatches. Current responses triggered by the application (1 s) of PB or GABA, or else their coapplication (PB + GABA), with application periods represented by open bars with the indicated concentrations (μM). Long solid bar marks the baseline. Short horizontal bars and arrowheads indicate the plateau and tail current amplitudes, respectively. The application period was >30 s. (Inset) Graph of calculated fraction blocked derived from the plateau and tail current amplitudes as in Fig. 4 A, with PB alone or coapplication of PB and GABA (means ± SEM; n = 4; see Results).