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. Author manuscript; available in PMC: 2010 Jan 15.
Published in final edited form as: Spine (Phila Pa 1976). 2009 Jan 15;34(2):E94–100. doi: 10.1097/BRS.0b013e31818b88a5

Figure 2.

Figure 2

Genome-wide linkage analysis of family 6061. (A) Two-point linkage analysis considering individuals with AIS and PE as affected was performed assuming autosomal dominant inheritance with penetrance of 80%, phenocopy rate of 1%, and disease allele frequency of 0.1%. (B) Multipoint linkage analysis considering individuals with AIS and PE as affected using the same parameters as above. Analysis was performed with marker sets of 100. (C) Multipoint linkage analysis considering individuals with AIS as affected using the same parameters.