FIG. 2.

Overview of EPC mobilization and homing. Contribution of BM EPCs to wound healing involves two critical events. BM EPCs are released from their niche into the circulation (mobilization). The circulating EPCs are recruited (homing) to injured tissue and contribute to neovascularization and wound healing. Mobilization and homing are controlled by different mechanisms. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article at www.liebertonline.com/ars).