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. 2003 Nov 3;100(23):13453–13458. doi: 10.1073/pnas.2230460100

Fig. 1.

Fig. 1.

Defect in BM B cell maturation in IFN-β-/- mice. BM cells, harvested from IFN-β+/+ and IFN-β-/- mice, were depleted of RBC and analyzed by flow cytometry after labeling with the indicated Abs. (A) B220- and CD43-lineage cells. B220-positive cells are shown subdivided into fractions I (B220+ve/CD43+ve), II (B220+ve/low/CD43-ve), and III (B220+ve/high/CD43-ve). (B-D) B220 and BP-1, IgM, and CD23 lineages. Where indicated, numbers represent the gated cell population as a percentage of total cell population. Data represent the mean from groups of five mice. *, P < 0.05; **, P < 0.01; ***, P < 0.001. +/+, IFN-β+/+; -/-, IFN-β-/-.