Immunoblot analysis of EhNP and recombinant COX-like protein. Polyclonal antibodies against the COX-like protein detected the 72- and 66-kDa protein bands in EhNP and recombinant COX-like protein. Lane 1, 300 ng of active sheep COX-1 enzyme; lane 2, 300 ng of sheep COX-2 enzyme; lane 3, 100 μg of EhNP; lane 4, 100 μg of Eh cytosol protein; lane 5, 50 μg of recombinant ameba COX-like protein; lane 6, 300 ng of active sheep COX-1 enzyme; lane 7, 300 ng of sheep COX-2 enzyme.