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Morphological changes in fibroblasts. Cell morphologies are shown at ×40 magnification. Shown are TIG-3 (A) and TIG-3 (B) infected with retroviral vectors expressing hTERT (T), SV40 ER (S), and H-RasV12 (R). (C) REF. (D) REF infected with retroviral vectors expressing S and R.
