Figure 3.

Placental transport of ⁴⁵Ca and ⁵¹Cr-EDTA in PTHrP knockout fetuses. The ratio of ⁴⁵Ca/⁵¹Cr activity accumulated in fetuses was determined (A) 5, (B) 15, and (C) 30 min after maternal administration of the isotopes. The mean heterozygote ⁴⁵Ca/⁵¹Cr ratio of each litter was set at 100% to allow the results of multiple litters to be compared. The number of observations is indicated in parentheses. WT, wild-type fetus. (A) ∗, P < 0.02 vs. HET; (B) ∗, P < 0.001 vs. HET; (C) ∗, P < 0.005 and ∗∗, P < 0.001 vs. HET.