Table 1. Grading of hyperthermia-induced seizures in α-syntrophin-null mice compared with WT mice.
Score | WT | α-Syn−/− | Description of the seizure (modified Racine scale) |
---|---|---|---|
6 | Death | ||
5 | ++ | Clonus, rearing, falling, and rapid leg contractions | |
4 | ++ | Clonus, rearing, and falling | |
3 | +++ | ++ | Clonus and rearing |
2 | ++++++ | + | Head nodding and forelimb clonus |
1 | + | ++ | Facial movement or silence |
0 | No response |
Each + represents one mouse.