Table 5.
Logistic regression analysis and effect of potential confounders on T2-lesion load volume
| Logistic regression equation | R2 | Q2/Q1 Odds ratio 95% CI | Q3/Q1 Odds ratio 95% CI | Q4/Q1 Odds ratio 95% CI | |
|---|---|---|---|---|---|
| RR/SP/CIS (N = 483) | T2LL = AODO + DD + DRB1*1501 | 0.15 | 1.90 | 1.69 | 1.32 |
| P= 0.015 | P= 0.049 | P = 0.314 | |||
| 1.13–3.20 | 1.00–2.86 | 0.77–2.29 | |||
| RR/SP/CIS (N = 483) | T2LL = AODO + DD + EDSS + DRB1*1501 | 0.18 | 1.92 | 1.74 | 1.38 |
| P= 0.014 | P= 0.039 | P = 0.258 | |||
| 1.14–3.23 | 1.03–2.94 | 0.79–2.40 | |||
| RR/SP/CIS (N = 482) | T2LL = AODO + TX + DD + DRB1*1501 | 0.19 | 1.97 | 1.76 | 1.39 |
| P= 0.012 | P= 0.038 | P = 0.245 | |||
| 1.16–3.33 | 1.03–3.00 | 0.80–2.43 | |||
| RR/SP/CIS (N = 482) | T2LL = AODO + TX + DD + EDSS + DRB1*1501 | 0.21 | 1.97 | 1.79 | 1.44 |
| P= 0.012 | P= 0.032 | P = 0.210 | |||
| 1.16–3.35 | 1.05–3.06 | 0.82–2.52 |
RR = relapsing-remitting MS; SP = secondary-progressive MS; CIS = clinically isolated syndrome; T2LL = T2-lesion load; AODO = age of disease onset; DD = disease duration; TX = exposure to MS treatment.
Significance of bold values is P≤0.05.