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. Author manuscript; available in PMC: 2009 Feb 10.
Published in final edited form as: Mol Ther. 2008 Jul 1;16(9):1587–1593. doi: 10.1038/mt.2008.140

Figure 7. Expression of ERα in ER-αKO hippocampal slices restores synaptic responses to β-estradiol 3-benzoate (EB).

Figure 7

EF1α-ERα lentivirus was injected unilaterally into the hippocampus and EF1α-GFP lentivirus was injected into the contralateral hippocampus of (a) female and (b) male ER-α knockout (ER-αKO) mice. Expression of estrogen receptor-α (ER-α) (filled circles) was associated with enhanced EB responsiveness relative to slices expressing green fluorescent protein (GFP) (open circles).