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. 2008 Nov 7;18(3):454–462. doi: 10.1093/hmg/ddn373

Figure 6.

Figure 6.

Cell autonomous effects of dUBE3A on dendritic branching in ddaE and ddaF neurons. (A) A control ddaE neuron labeled by GFP. (B) A ddaE neuron homozygous for the dUBE3AΔ3-8 allele. (C) A ddaE neuron homozygous for the dUBE3AΔ15-8 allele. The GFP-labeled ddaE neurons in (A–C) were generated by the MARCM technique. (D) Quantification of the number of dendritic branches of ddaE and ddaF neurons of different genotypes. (E) A wild-type ddaE and a wild-type ddaF neuron labeled by GFP under the control of Gal4221. (F) A ddaE and a ddaF neuron expressing UAS-dUBE3A RNAi (VDRC45876) driven by Gal4221. (G) A ddaE and a ddaF neuron expressing UAS-dUBE3A RNAi (VDRC45875) driven by Gal4221. (H) Quantification of the number of dendritic branches of ddaE and ddaF neurons expressing GFP and RNAi constructs. Values are mean ± SEM. *P < 0.05; ***P < 0.001.