Table 2.

Quantitative metrics of thinning by region within sample #1

Region	Mean thickness (mm) (SD)				Group mean	Percent	Effect size
	OC		Mild AD		Difference (mm)	Thinning
Medial temporal	2.91	(0.33)	2.51	(0.32)	0.40	13.62	1.22
Inferior temporal	2.67	(0.23)	2.36	(0.23)	0.31	11.46	1.33
Temporal pole	2.63	(0.21)	2.39	(0.20)	0.25	9.31	1.20
Angular	2.32	(0.16)	2.10	(0.24)	0.22	9.60	1.09
Superior frontal	2.55	(0.17)	2.35	(0.22)	0.20	7.83	1.02
Superior parietal	2.02	(0.13)	1.87	(0.14)	0.15	7.51	1.12
Supramarginal	2.38	(0.17)	2.18	(0.20)	0.20	8.43	1.08
Precuneus	2.21	(0.18)	2.03	(0.18)	0.18	8.07	0.99
Inferior frontal	2.16	(0.13)	2.01	(0.15)	0.15	6.96	1.07
Primary visual	1.51	(0.12)	1.48	(0.14)	0.03	2.29	0.27

Note: Effect size = Cohen's d effect size. All regions are significantly thinner in AD than OC (P < 0.01) except for primary visual, which is not statistically different between OC and AD groups.