Table 4.
Region | Mean thickness (mm) (SD) |
Percent thinning (vs. OC) |
Effect Size (vs. OC) |
|||||||
OC | Incipient AD | Very mild AD | Incipient AD | Very mild AD | Incipient AD | Very mild AD | ||||
Medial temporal | 2.91 | (0.33) | 2.80 | (0.30) | 2.63 | (0.37) | 3.89V,A | 9.65C,I | 0.36 | 0.80 |
Inferior temporal | 2.67 | (0.23) | 2.62 | (0.23) | 2.53 | (0.20) | 1.69A | 4.97C,A | 0.19 | 0.60 |
Temporal pole | 2.63 | (0.21) | 2.55 | (0.24) | 2.52 | (0.21) | 3.14A | 4.39C,A | 0.37 | 0.55 |
Angular | 2.32 | (0.16) | 2.21 | (0.18) | 2.16 | (0.14) | 4.46C,A | 6.39C | 0.61 | 1.06 |
Superior frontal | 2.55 | (0.17) | 2.49 | (0.20) | 2.43 | (0.19) | 2.29A | 4.84C | 0.31 | 0.67 |
Superior parietal | 2.02 | (0.13) | 1.98 | (0.18) | 1.92 | (0.13) | 2.08A | 5.12C | 0.27 | 0.80 |
Supramarginal | 2.38 | (0.17) | 2.28 | (0.18) | 2.26 | (0.18) | 3.88C,A | 4.89C | 0.53 | 0.67 |
Precuneus | 2.21 | (0.18) | 2.15 | (0.28) | 2.08 | (0.22) | 2.43A | 5.84C | 0.23 | 0.64 |
Inferior frontal | 2.16 | (0.13) | 2.14 | (0.14) | 2.03 | (0.19) | 1.15V,A | 6.28C,I | 0.19 | 0.85 |
Primary visual | 1.51 | (0.12) | 1.52 | (0.16) | 1.50 | (0.12) | −0.39 | 0.89 | −0.04 | 0.11 |
Note: Superscripts indicate that the group is significantly different from OC (C), incipient AD (I), very mild AD (V), or mild AD (A) (P < 0.05, uncorrected). Percent thinning is in comparison to OC group (data presented in Table 3). Effect size is Cohen's d.