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. 2008 Jul 16;19(3):497–510. doi: 10.1093/cercor/bhn113

Table 4.

Quantitative metrics of thinning by region within incipient and very mild AD participants

Region Mean thickness (mm) (SD)
Percent thinning (vs. OC)
Effect Size (vs. OC)
OC Incipient AD Very mild AD Incipient AD Very mild AD Incipient AD Very mild AD
Medial temporal 2.91 (0.33) 2.80 (0.30) 2.63 (0.37) 3.89V,A 9.65C,I 0.36 0.80
Inferior temporal 2.67 (0.23) 2.62 (0.23) 2.53 (0.20) 1.69A 4.97C,A 0.19 0.60
Temporal pole 2.63 (0.21) 2.55 (0.24) 2.52 (0.21) 3.14A 4.39C,A 0.37 0.55
Angular 2.32 (0.16) 2.21 (0.18) 2.16 (0.14) 4.46C,A 6.39C 0.61 1.06
Superior frontal 2.55 (0.17) 2.49 (0.20) 2.43 (0.19) 2.29A 4.84C 0.31 0.67
Superior parietal 2.02 (0.13) 1.98 (0.18) 1.92 (0.13) 2.08A 5.12C 0.27 0.80
Supramarginal 2.38 (0.17) 2.28 (0.18) 2.26 (0.18) 3.88C,A 4.89C 0.53 0.67
Precuneus 2.21 (0.18) 2.15 (0.28) 2.08 (0.22) 2.43A 5.84C 0.23 0.64
Inferior frontal 2.16 (0.13) 2.14 (0.14) 2.03 (0.19) 1.15V,A 6.28C,I 0.19 0.85
Primary visual 1.51 (0.12) 1.52 (0.16) 1.50 (0.12) −0.39 0.89 −0.04 0.11

Note: Superscripts indicate that the group is significantly different from OC (C), incipient AD (I), very mild AD (V), or mild AD (A) (P < 0.05, uncorrected). Percent thinning is in comparison to OC group (data presented in Table 3). Effect size is Cohen's d.