Table 3.
Regression of Baseline (1995–1996) and Follow-up (2001–2006) Leukocyte Telomere Length on Parameters of Interest for Participants in the Bogalusa Heart Study in Louisianaa
| Parameter | Baseline LTL |
Follow-up LTL |
||||||
| β Coefficient | P Value | Partial R2 | Model R2 | β Coefficient | P Value | Partial R2 | Model R2 | |
| Race, African American | 587.8 | <0.0001 | 0.107 | 551.5 | <0.0001 | 0.096 | ||
| Age, years | −13.4 | 0.0220 | 0.009 | −11.7 | 0.0715 | 0.005 | ||
| BMI, kg/m2 | −9.1 | 0.0316 | 0.006 | −8.6 | 0.0312 | 0.007 | ||
| Smoking, yes/no | −141.6 | 0.0227 | 0.006 | −163.5 | 0.0099 | 0.008 | ||
| Sex, female | 56.8 | 0.3456 | 0.002 | 0.130 | 37.0 | 0.5372 | 0.000 | 0.116 |
Abbreviations: BMI, body mass index; LTL, leukocyte telomere length (expressed in base pairs (bp)).
The rate of change in LTL (bp/year) is negative; therefore, negative regression coefficients denote faster LTL attrition.